Jean-Pierre Sauvage’s Molecular Machines

  If you look about biological field, “molecular motors” or “machines” have a crucial roles. These systems are composed of multi components involving large amplitude for geometrical changes or locomotion of only one component of the system. These both attitudes are under the action of an external stimuli which can be a variation of pH, Redox process, etc.

Molecular Motors consist of several units:

  • One without any motion called the rotor
  • All the other parts move, called the stator

It’s like the fuel similar in biological systems to the ATP.

Linear motors and rotary motors have been both studied. Whereas linear motors are know for many years, rotary motors has required lot of works by Pr Jean-Pierre Sauvage and his lab team, where they have identified then investiged this kinds of motors.

One of the most popular and extraordinary rotatory motors is the ATPase: look at the picture over the text.

ATPase is the stator called c and γ and the rotor is made with six proteins αβ.

In order that, whereas the subunit of the rotor according to a pH gradient, there is production of ATP!

   On the schema, the biological rotary is called γ and c: the mobile portion. And the six proteins αβ which form the stator of the motor are motionless.

References: Pr JP Sauvage Works

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One thought on “Jean-Pierre Sauvage’s Molecular Machines

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